In Vivo ZIMIR Imaging of Mouse Pancreatic Islet Cells Shows Oscillatory Insulin Secretion

In Vivo ZIMIR Imaging of Mouse Pancreatic Islet Cells Shows Oscillatory Insulin Secretion

Appropriate insulin secretion is essential for maintaining euglycemia, and impairment or loss of insulin release represents a causal event leading to diabetes. There have been extensive efforts of studying insulin secretion and its regulation using a variety of biological preparations, yet it remain...

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Bibliographic Details
Main Authors: Shiuhwei Chen, ZhiJiang Huang, Harrison Kidd, Min Kim, Eul Hyun Suh, Shangkui Xie, Ebrahim H. Ghazvini Zadeh, Yan Xu, A. Dean Sherry, Philipp E. Scherer, Wen-hong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
insulin oscillation
ZIMIR
ZIGIR
HaloTag
intravital microscopy (IVM)
beta cell mass
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.613964/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.613964/full

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