Epigenetic silencing of KLF2 by long non-coding RNA SNHG1 inhibits periodontal ligament stem cell osteogenesis differentiation

Epigenetic silencing of KLF2 by long non-coding RNA SNHG1 inhibits periodontal ligament stem cell osteogenesis differentiation

Abstract Background Exploring the effects of lncRNA SNHG1 in the process of osteogenic differentiation of periodontal ligament stem cells (PDLSCs) would provide novel therapeutic strategies for tissue regeneration. Methods Loss-of-function and gain-of-function assays were induced by lentivirus. The...

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Bibliographic Details
Main Authors: Zhaobao Li, Xiangjun Guo, Shuainan Wu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Stem Cell Research & Therapy
Subjects:
SNHG1
EZH2
KLF2
PDLSCs
Osteogenic differentiation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01953-8

Internet

http://link.springer.com/article/10.1186/s13287-020-01953-8

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