High Notch1 expression affects chemosensitivity of head and neck squamous cell carcinoma to paclitaxel and cisplatin treatment

High Notch1 expression affects chemosensitivity of head and neck squamous cell carcinoma to paclitaxel and cisplatin treatment

Background: Notch1 expression has been reported to be associated with chemotherapy resistance and poor prognosis, but the role of Notch1 in head and neck squamous cell carcinoma (HNSCC) sensitivity to anticancer drugs remains unclear. The aim of this study was to evaluate HNSCC sensitivity to paclit...

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Bibliographic Details
Main Authors: Zuping Zhang, Zhongxin Zhou, Mingde Zhang, Neil Gross, Lili Gong, Shihong Zhang, Dapeng Lei, Qiang Zeng, Xiaoning Luo, Guojun Li, Xuezhong Li
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Head and neck cancers
Squamous cell carcinomas
Paclitaxel
Cisplatin
Chemosensitivity
Notch1 expression
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219321419

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http://www.sciencedirect.com/science/article/pii/S0753332219321419

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