Analgesia Effect of Enteric Sustained-Release Tetrodotoxin Pellets in the Rat

Tetrodotoxin (TTX) was identified as a latent neurotoxin that has a significant analgesia effect. It was rapidly absorbed and excreted in rat after intramuscular (i.m.) injection. To maintain the effect, frequent injections were required. The enteric sustained-release TTX pellets with sucrose pellet...

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Bibliographic Details
Main Authors: Bihong Hong, Jianlin He, Jipeng Sun, Qingqing Le, Kaikai Bai, Yanhua Mou, Yiping Zhang, Weizhu Chen, Wenwen Huang
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/12/1/32