TAU OLIGOMERS AS DIRECT TARGETS FOR ALZHEIMER´S DIAGNOSIS AND NOVEL DRUGS

A cumulative number of approaches have been carried out to elucidate the pathogenesis of Alzheimer´s disease (AD). Tangle formation has been identified as a major event involved in the neurodegenerative process, due to the conversion of either soluble peptides or oligomers into insoluble fi...

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Bibliographic Details
Main Authors: Leonardo eGuzman-Martinez, Gonzalo A. eFarias, Ricardo Benjamin Maccioni
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Neurology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00167/full