Cystatin C regulates the cytotoxicity of infection‐induced endothelial‐derived β‐amyloid

Cystatin C regulates the cytotoxicity of infection‐induced endothelial‐derived β‐amyloid

Infection of rat pulmonary microvascular endothelial cells with the bacterium Pseudomonas aeruginosa induces the production and release of cytotoxic oligomeric tau and beta amyloid (Aβ). Here, we characterized these cytotoxic amyloids. Cytotoxic behavior and oligomeric tau were partially resistant t...

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Bibliographic Details
Main Authors: Ron Balczon, Kyle A. Morrow, Silas Leavesley, Christopher M. Francis, Trevor C. Stevens, Ezinne Agwaramgbo, Christopher Williams, Reece P. Stevens, Geri Langham, Sarah Voth, Eugene A. Cioffi, Susan E. Weintraub, Troy Stevens
Format: Article
Language:English
Published: Wiley 2020-11-01
Series:FEBS Open Bio
Subjects:
Aβ
cystatin C
endothelial cell
pneumonia
Pseudomonas aeruginosa
Tau protein
Online Access:https://doi.org/10.1002/2211-5463.12997

Internet

https://doi.org/10.1002/2211-5463.12997

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