Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial

Development of a standardized definition for clinically significant bleeding in the ASPirin in Reducing Events in the Elderly (ASPREE) trial

Background: Bleeding is the major risk of aspirin treatment, especially in the elderly. A consensus definition for clinically significant bleeding (CSB) in aspirin primary prevention trials is lacking in the literature. Methods: This paper details the development, modification, application, and qual...

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Bibliographic Details
Main Authors: Karen L. Margolis, Suzanne E. Mahady, Mark R. Nelson, Diane G. Ives, Suzanne Satterfield, Carlene Britt, Saifuddin Ekram, Jessica Lockery, Erin C. Schwartz, Robyn L. Woods, John J. McNeil, Erica M. Wood
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865418300152

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http://www.sciencedirect.com/science/article/pii/S2451865418300152

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