Fosmanogepix: A Review of the First-in-Class Broad Spectrum Agent for the Treatment of Invasive Fungal Infections

Fosmanogepix is a first-in-class antifungal currently in Phase 2 clinical trials for the treatment of invasive fungal infections caused by <i>Candida, Aspergillus </i>and rare molds. Fosmanogepix is the N-phosphonooxymethylene prodrug of manogepix, an inhibitor of the fungal enzyme Gwt1....

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Bibliographic Details
Main Authors: Karen Joy Shaw, Ashraf S. Ibrahim
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Journal of Fungi
Subjects:
MGX
Online Access:https://www.mdpi.com/2309-608X/6/4/239