Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.

Myb-binding protein 1A (MYBBP1A) is essential for early embryonic development, controls cell cycle and mitosis, and acts as a tumor suppressor.

MYBBP1A is a predominantly nucleolar transcriptional regulator involved in rDNA synthesis and p53 activation via acetylation. However little further information is available as to its function. Here we report that MYBBP1A is developmentally essential in the mouse prior to blastocyst formation. In ce...

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Bibliographic Details
Main Authors: Silvia Mori, Rosa Bernardi, Audrey Laurent, Massimo Resnati, Ambra Crippa, Arianna Gabrieli, Rebecca Keough, Thomas J Gonda, Francesco Blasi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466261?pdf=render

Internet

http://europepmc.org/articles/PMC3466261?pdf=render

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