DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

While DNA methylation and gene expression data are widely available for animal models, comprehensive data from human development is rarer. Here, the authors generated transcriptional and DNA methylation data from 21 organs during human development and 6 isogenic induced pluripotent stem cell lines.

Bibliographic Details
Main Authors: Matthias S. Roost, Roderick C. Slieker, Monika Bialecka, Liesbeth van Iperen, Maria M. Gomes Fernandes, Nannan He, H. Eka D. Suchiman, Karoly Szuhai, Françoise Carlotti, Eelco J. P. de Koning, Christine L. Mummery, Bastiaan T. Heijmans, Susana M. Chuva de Sousa Lopes
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01077-3

Internet

https://doi.org/10.1038/s41467-017-01077-3

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