Quorum quenching activity of Andrographis paniculata (Burm f.) Nees andrographolide compounds on metallo-β-lactamase-producing clinical isolates of Pseudomonas aeruginosa PA22 and PA247 and their effect on lasR gene expression

Quorum quenching activity of Andrographis paniculata (Burm f.) Nees andrographolide compounds on metallo-β-lactamase-producing clinical isolates of Pseudomonas aeruginosa PA22 and PA247 and their effect on lasR gene expression

Andrographis paniculata (Burm f.) Nees is a tropical plant native to Southeast Asia that has been used as an effective remedy for a wide variety of illnesses in traditional Chinese and Ayurvedic medicine. The antimicrobial activity of its crude extract had been shown to be due to its quorum quenchin...

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Bibliographic Details
Main Authors: An Margarete Tan Lim, Glenn G. Oyong, Maria Carmen S. Tan, Chien Chang Shen, Consolacion Y. Ragasa, Esperanza C. Cabrera
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Heliyon
Subjects:
Andrographis paniculata
Pseudomonas aeruginosa
Quorum sensing
Biofilm
Protease
Swarming
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021011051

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http://www.sciencedirect.com/science/article/pii/S2405844021011051

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