Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening

Establishment and maintenance of apico-basal polarity in epithelial organs needs to be tightly coupled with cell division. Here the authors show that the Rab35 GTPase tethers intracellular vesicles containing key apical determinants at the cleavage site, connecting cytokinesis to apico-basal polarit...

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Bibliographic Details
Main Authors: Kerstin Klinkert, Murielle Rocancourt, Anne Houdusse, Arnaud Echard
Format: Article
Language:English
Published: Nature Publishing Group 2016-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms11166