Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets

Glioblastoma (GBM), a WHO-defined Grade IV astrocytoma, is the most common and aggressive CNS malignancy. Despite current treatment modalities, the survival time remains dismal. The main cause of mortality in patients with this disease is reoccurrence of the malignancy, which is attributed to treatm...

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Bibliographic Details
Main Authors: Meena Jhanwar-Uniyal, Michael Labagnara, Marissa Friedman, Amanda Kwasnicki, Raj Murali
Format: Article
Language:English
Published: MDPI AG 2015-03-01
Series:Cancers
Subjects:
GBM
Online Access:http://www.mdpi.com/2072-6694/7/2/538