Effects of Diphenyl Diselenide on Methylmercury Toxicity in Rats

This study investigates the efficacy of diphenyl diselenide [(PhSe)2] in attenuating methylmercury- (MeHg-)induced toxicity in rats. Adult rats were treated with MeHg [5 mg/kg/day, intragastrically (i.g.)] and/ or (PhSe)2 [1 mg/kg/day, intraperitoneally (i.p.)] for 21 days. Body weight gain and moto...

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Bibliographic Details
Main Authors: Cristiane L. Dalla Corte, Caroline Wagner, Jéssie H. Sudati, Bruna Comparsi, Gerlania O. Leite, Alcindo Busanello, Félix A. A. Soares, Michael Aschner, João B. T. Rocha
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2013/983821