Discovery and characterization of variance QTLs in human induced pluripotent stem cells.

Quantification of gene expression levels at the single cell level has revealed that gene expression can vary substantially even across a population of homogeneous cells. However, it is currently unclear what genomic features control variation in gene expression levels, and whether common genetic var...

Full description

Bibliographic Details
Main Authors: Abhishek K Sarkar, Po-Yuan Tung, John D Blischak, Jonathan E Burnett, Yang I Li, Matthew Stephens, Yoav Gilad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008045