E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation

E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation

Abstract Electronic cigarette (e-cig) vaping is increasing rapidly in the United States, as e-cigs are considered less harmful than combustible cigarettes. However, limited research has been conducted to understand the possible mechanisms that mediate toxicity and pulmonary health effects of e-cigs....

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Bibliographic Details
Main Authors: Qixin Wang, Isaac K. Sundar, Dongmei Li, Joseph H. Lucas, Thivanka Muthumalage, Samantha R. McDonough, Irfan Rahman
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Respiratory Research
Subjects:
E-cig exposure
nAChRα7
Inflammation
Dysregulated repair
Extracellular matrix
Online Access:http://link.springer.com/article/10.1186/s12931-020-01396-y

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http://link.springer.com/article/10.1186/s12931-020-01396-y

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