Novel Formulations of C-Peptide with Long-Acting Therapeutic Potential for Treatment of Diabetic Complications

Novel Formulations of C-Peptide with Long-Acting Therapeutic Potential for Treatment of Diabetic Complications

The development and application of novel nanospheres based on cationic and anionic random amphiphilic polypeptides with prolonged stability were proposed. The random copolymers, e.g., poly(l-lysine-co-d-phenylalanine) (P(Lys-co-dPhe)) and poly(l-glutamic acid-co-d-phenylalanine) (P(Glu-co-dPhe)), wi...

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Bibliographic Details
Main Authors: Natalia Zashikhina, Vladimir Sharoyko, Mariia Antipchik, Irina Tarasenko, Yurii Anufrikov, Antonina Lavrentieva, Tatiana Tennikova, Evgenia Korzhikova-Vlakh
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceutics
Subjects:
polypeptides
amphiphilic random copolymers
nanoparticles
C-peptide
encapsulation
diabetes
Online Access:http://www.mdpi.com/1999-4923/11/1/27

Internet

http://www.mdpi.com/1999-4923/11/1/27

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