Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma

Programmed cell death ligand 1 cut-point is associated with reduced disease specific survival in resected pancreatic ductal adenocarcinoma

Abstract Background Programmed cell death 1 (PD1) inhibitors have recently shown promising anti-cancer effects in a number of solid tumor types. A predictive biomarker to this class of drugs has not been clearly identified; however, overexpression of the PD1 ligand (PD-L1) has shown particular promi...

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Bibliographic Details
Main Authors: Basile Tessier-Cloutier, Steve E. Kalloger, Mohammad Al-Kandari, Katy Milne, Dongxia Gao, Brad H. Nelson, Daniel J. Renouf, Brandon S. Sheffield, David F. Schaeffer
Format: Article
Language:English
Published: BMC 2017-09-01
Series:BMC Cancer
Subjects:
Pancreatic cancer
Programmed cell death 1 ligand
DNA mismatch repair
Tumor-infiltrating lymphocytes
Biomarkers
Immuno-oncology
Online Access:http://link.springer.com/article/10.1186/s12885-017-3634-5

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http://link.springer.com/article/10.1186/s12885-017-3634-5

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