Venetoclax in Combination with Decitabine for Relapsed T-Cell Acute Lymphoblastic Leukemia after Allogeneic Hematopoietic Cell Transplant

Long-term disease-free survival in adults with T-cell acute lymphoblastic leukemia (T-ALL) remains poor, particularly after relapse, with few available salvage options. Preclinical data suggest that inhibition of the antiapoptotic protein BCL-2 (B-cell lymphoma 2) either alone or in combination with...

Full description

Bibliographic Details
Main Authors: Leena T. Rahmat, Anna Nguyen, Haifaa Abdulhaq, Sonam Prakash, Aaron C. Logan, Gabriel N. Mannis
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2018/6092646