Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling

Abstract Primary aldosteronism (PA) is the most frequent form of secondary arterial hypertension. Mutations in different genes increase aldosterone production in PA, but additional mechanisms may contribute to increased cell proliferation and aldosterone producing adenoma (APA) development. We perfo...

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Bibliographic Details
Main Authors: Rami M. El Zein, Audrey H. Soria, Jose Felipe Golib Dzib, Amanda J. Rickard, Fabio L. Fernandes-Rosa, Benoit Samson-Couterie, Isabelle Giscos-Douriez, Angélique Rocha, Marko Poglitsch, Celso E. Gomez-Sanchez, Laurence Amar, Norbert B. Ghyselinck, Arndt Benecke, Maria-Christina Zennaro, Sheerazed Boulkroun
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50988-2

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https://doi.org/10.1038/s41598-019-50988-2

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