Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients.

Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients.

T helper 17 cells (T(H)-17) represent a lineage of effector T cells critical in host defence and autoimmunity. In both mouse and human IL-1β has been indicated as a key cytokine for the commitment to T(H)-17 cells. Cryopyrin-associated periodic syndromes (CAPS) are a group of inflammatory diseases a...

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Bibliographic Details
Main Authors: Denise Lasigliè, Elisabetta Traggiai, Silvia Federici, Maria Alessio, Antonella Buoncompagni, Andrea Accogli, Sabrina Chiesa, Federica Penco, Alberto Martini, Marco Gattorno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3102666?pdf=render

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http://europepmc.org/articles/PMC3102666?pdf=render

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