H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots

H2AK121ub in Arabidopsis associates with a less accessible chromatin state at transcriptional regulation hotspots

Polycomb Group complexes maintain gene repression through the incorporation of H2AK121ub and H3K27me3. Here, the authors show that H2AK121ub marks less accessible but transcriptionally permissive chromatin, while H3K27me3 enforces a repressed transcriptionally less-permissive state.

Bibliographic Details
Main Authors: Xiaochang Yin, Francisco J. Romero-Campero, Pedro de Los Reyes, Peng Yan, Jing Yang, Guangmei Tian, XiaoZeng Yang, Xiaorong Mo, Shuangshuang Zhao, Myriam Calonje, Yue Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20614-1

Internet

https://doi.org/10.1038/s41467-020-20614-1

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