FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

FTR83, a Member of the Large Fish-Specific finTRIM Family, Triggers IFN Pathway and Counters Viral Infection

Tripartite motif (TRIM) proteins are involved in various cellular functions and constitute key factors of the antiviral innate immune response. TRIM proteins can bind viral particles directly, sending them to degradation by the proteasome, or ubiquitinate signaling molecules leading to upregulation...

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Bibliographic Details
Main Authors: Christelle Langevin, Elina Aleksejeva, Armel Houel, Valérie Briolat, Corinne Torhy, Aurélie Lunazzi, Jean-Pierre Levraud, Pierre Boudinot
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Immunology
Subjects:
FTR83
finTRIM
interferon
antiviral immunity
zebrafish
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00617/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00617/full

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