Modulation of Entrapment Efficiency and In Vitro Release Properties of BSA-Loaded Chitosan Microparticles Cross-Linked with Citric Acid as a Potential Protein–Drug Delivery System

Modulation of Entrapment Efficiency and In Vitro Release Properties of BSA-Loaded Chitosan Microparticles Cross-Linked with Citric Acid as a Potential Protein–Drug Delivery System

Microparticles, aimed for oral protein and peptide drug delivery, were prepared via emulsion cross-linking using citric acid as cross-linker and polyglycerol polyricinoleate as surfactant. A comparative study of the interaction between chitosan and citric acid and its effect on the resulting micropa...

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Bibliographic Details
Main Authors: Natalia Sedyakina, Andrey Kuskov, Kelly Velonia, Nataliya Feldman, Sergey Lutsenko, Grigory Avramenko
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Materials
Subjects:
chitosan microparticles
citric acid
cross-linker
polyglycerol polyricinoleate
controlled release
protein delivery
Online Access:https://www.mdpi.com/1996-1944/13/8/1989

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https://www.mdpi.com/1996-1944/13/8/1989

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