Assessment of Global DNA Methylation in Stem Cells with Reverse-Phase High Performance Liquid Chromatography

Assessment of Global DNA Methylation in Stem Cells with Reverse-Phase High Performance Liquid Chromatography

Objective: We tested the possibility of the use of reverse-phase high performance liquid chromatography (RP-HPLC), a sensitive, simple and cost effective technique, for evaluation of global DNA methylation alteration in stem cells. Methods: We detected genomic methylation in four cell lines of m...

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Bibliographic Details
Main Authors: Tatsanee Phermthai, Suphakde Julavijitphong, Yuparat OdGlun, Nednapis Tirawanchai, Decha Silpsorn, Surin Khunyok, Cindy Tian
Format: Article
Language:English
Published: Mahidol University 2020-07-01
Series:Siriraj Medical Journal
Subjects:
DNA methylation
epigenetics
methyl cytidine
reverses phase-HPLC
stem cells
Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244151

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https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244151

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