A Novel Panel of Rabbit Monoclonal Antibodies and Their Diverse Applications Including Inhibition of <i>Clostridium perfringens</i> Epsilon Toxin Oligomerization

A Novel Panel of Rabbit Monoclonal Antibodies and Their Diverse Applications Including Inhibition of <i>Clostridium perfringens</i> Epsilon Toxin Oligomerization

The pore-forming epsilon toxin (ETX) produced by <i>Clostridium perfringens</i> is among the most lethal bacterial toxins known. Sensitive antibody-based reagents are needed to detect toxin, distinguish mechanisms of cell death, and prevent ETX toxicity. Using B-cell immuno-panning and c...

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Bibliographic Details
Main Authors: Jennifer R. Linden, Kiel Telesford, Samantha Shetty, Paige Winokour, Sylvia Haigh, Ellen Cahir-McFarland, Giovanna Antognetti, Abhishek Datta, Tao Wang, Werner Meier, Timothy Vartanian
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Antibodies
Subjects:
<i>Clostridium perfringens</i>
epsilon toxin
epsilon protoxin
neutralizing
antibodies
oligomerization
pore formation
Online Access:https://www.mdpi.com/2073-4468/7/4/37

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https://www.mdpi.com/2073-4468/7/4/37

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