Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells

Depletion of ATP-Citrate Lyase (ATPCL) Affects Chromosome Integrity Without Altering Histone Acetylation in Drosophila Mitotic Cells

The Citrate Lyase (ACL) is the main cytosolic enzyme that converts the citrate exported from mitochondria by the SLC25A1 carrier in Acetyl Coenzyme A (acetyl-CoA) and oxaloacetate. Acetyl-CoA is a high-energy intermediate common to a large number of metabolic processes including protein acetylation...

Full description

Bibliographic Details
Main Authors: Patrizia Morciano, Maria Laura Di Giorgio, Antonella Porrazzo, Valerio Licursi, Rodolfo Negri, Yikang Rong, Giovanni Cenci
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Physiology
Subjects:
citrate lyase
Drosophila chromosomes
histone acetylation
acetyl-CoA
Drosophila
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00383/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00383/full

Similar Items