scAI: an unsupervised approach for the integrative analysis of parallel single-cell transcriptomic and epigenomic profiles

Abstract Simultaneous measurements of transcriptomic and epigenomic profiles in the same individual cells provide an unprecedented opportunity to understand cell fates. However, effective approaches for the integrative analysis of such data are lacking. Here, we present a single-cell aggregation and...

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Bibliographic Details
Main Authors: Suoqin Jin, Lihua Zhang, Qing Nie
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-020-1932-8