Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine.

Cervical cancer is a common type of cancer among women worldwide and infection with high-risk human papillomavirus (HPVs) types represents the major risk factor for the etiopathogenesis of the disease. HPV-16 is the most frequently identified HPV type in cervical lesions and expression of E6 and E7...

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Main Authors: Liliane Maria Fernandes de Oliveira, Mirian Galliote Morale, Agatha A Muniz Chaves, Aline Marques Cavalher, Aline Soriano Lopes, Mariana de Oliveira Diniz, Alessandra Soares Schanoski, Robson Lopes de Melo, Luís Carlos de Souza Ferreira, Maria Leonor S de Oliveira, Marilene Demasi, Paulo Lee Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4577214?pdf=render