A Bayesian Framework that integrates heterogeneous data for inferring gene regulatory networks

Reconstruction of gene regulatory networks (GRNs) from experimental data is a fundamental challenge in systems biology. A number of computational approaches have been developed to infer GRNs from mRNA expression profiles. However, expression profiles alone are proving to be insufficient for inferrin...

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Bibliographic Details
Main Author: Tapesh eSantra
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2014.00013/full