MicroRNA-135a regulates NHE9 to inhibit proliferation and migration of glioblastoma cells

MicroRNA-135a regulates NHE9 to inhibit proliferation and migration of glioblastoma cells

Abstract Background Glioblastoma multiformae (GBM) is the most aggressive type of malignant brain tumor with complex molecular profile. Overexpression of Na+/H+ Exchanger isoform 9 (NHE9) promotes tumor progression and correlates positively with insensitivity to radiochemotherapy and poor prognosis....

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Bibliographic Details
Main Authors: Daniela M. Gomez Zubieta, Mohamed A. Hamood, Rami Beydoun, Ashley E. Pall, Kalyan C. Kondapalli
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Cell Communication and Signaling
Subjects:
Sodium-proton exchange
NHE9
SLC9A9
pH
Endosome
Glioma
Online Access:http://link.springer.com/article/10.1186/s12964-017-0209-7

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http://link.springer.com/article/10.1186/s12964-017-0209-7

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