Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix

Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix

Osteoporosis is a bone metabolic disease caused by the imbalance between osteoblasts and osteoclasts due to excess osteoclastogenesis, manifesting in the decrease of bone density and bone strength. Scutellariae Radix shows good anti-osteoporosis activity, but the effective component is still unclear...

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Bibliographic Details
Main Authors: Yanqiu Gu, Xiao Chen, Yao Wang, Yue Liu, Leyi Zheng, Xiaoqun Li, Rong Wang, Shaozhan Wang, Shengnan Li, Yifeng Chai, Jiacan Su, Yongfang Yuan, Xiaofei Chen
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Acta Pharmaceutica Sinica B
Subjects:
3-Mercaptopropyltrimethoxysilane-modifiedsilica
Two-dimensional cell membrane chromatography
Scutellariae Radix
Anti-osteoporosis
Tectochrysin
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383519310068

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http://www.sciencedirect.com/science/article/pii/S2211383519310068

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