TNF-Signaling Modulates Neutrophil-Mediated Immunity at the Feto-Maternal Interface During LPS-Induced Intrauterine Inflammation

TNF-Signaling Modulates Neutrophil-Mediated Immunity at the Feto-Maternal Interface During LPS-Induced Intrauterine Inflammation

Accumulation of activated neutrophils at the feto-maternal interface is a defining hallmark of intrauterine inflammation (IUI) that might trigger an excessive immune response during pregnancy. Mechanisms responsible of this massive neutrophil recruitment are poorly investigated. We have previously s...

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Bibliographic Details
Main Authors: Pietro Presicce, Monica Cappelletti, Paranthaman Senthamaraikannan, Feiyang Ma, Marco Morselli, Courtney M. Jackson, Shibabrata Mukherjee, Lisa A. Miller, Matteo Pellegrini, Alan H. Jobe, Claire A. Chougnet, Suhas G. Kallapur
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
chorioamnionitis
neutrophils
inflammation
innate immunity
reproductive immunology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00558/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00558/full

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