Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.

Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection.

High expression of CD161 on CD8+ T cells is associated with a population of cells thought to play a role in mucosal immunity. We wished to investigate this subset in an HIV and Mycobacterium tuberculosis (MTB) endemic African setting.A flow cytometric approach was used to assess the frequency and ph...

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Bibliographic Details
Main Authors: Emily B Wong, Ngomu Akeem Akilimali, Pamla Govender, Zuri A Sullivan, Cormac Cosgrove, Mona Pillay, David M Lewinsohn, William R Bishai, Bruce D Walker, Thumbi Ndung'u, Paul Klenerman, Victoria O Kasprowicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3877057?pdf=render

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http://europepmc.org/articles/PMC3877057?pdf=render

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