Regulatory hotspots in the malaria parasite genome dictate transcriptional variation.

The determinants of transcriptional regulation in malaria parasites remain elusive. The presence of a well-characterized gene expression cascade shared by different Plasmodium falciparum strains could imply that transcriptional regulation and its natural variation do not contribute significantly to...

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Bibliographic Details
Main Authors: Joseph M Gonzales, Jigar J Patel, Napawan Ponmee, Lei Jiang, Asako Tan, Steven P Maher, Stefan Wuchty, Pradipsinh K Rathod, Michael T Ferdig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2553844?pdf=render