Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1

Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1

Disruption of endothelial monolayer integrity is the primary instigating factor for many cardiovascular diseases. High density lipoprotein (HDL) oxidized by heme enzyme myeloperoxidase (MPO) is dysfunctional in promoting endothelial repair. Apolipoprotein A-1 mimetic 4F with its pleiotropic benefits...

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Bibliographic Details
Main Authors: Dan He, Mingming Zhao, Congying Wu, Wenjing Zhang, Chenguang Niu, Baoqi Yu, Jingru Jin, Liang Ji, Belinda Willard, Anna V. Mathew, Y. Eugene Chen, Subramaniam Pennathur, Huiyong Yin, Yuan He, Bing Pan, Lemin Zheng
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
ApoA-1
4F
Endothelial repair
Oxidized HDL
Re-endothelialization
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171730722X

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http://www.sciencedirect.com/science/article/pii/S221323171730722X

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