Bone Marrow-Derived Conventional, But Not Cloned, Mesenchymal Stem Cells Suppress Lymphocyte Proliferation and Prevent Graft-Versus-Host Disease in Rats

Bone marrow-derived mesenchymal stem cells (MSCs) could exert a potent immunosuppressive effect, and therefore may have a therapeutic potential in T-cell-dependent pathologies. In the present study, we aimed to determine whether MSCs could be used to control graft-versus-host disease (GvHD), a major...

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Bibliographic Details
Main Authors: Yusuke Kitazawa, Xiao-Kang Li M.D., Ph.D., Lin Xie, Ping Zhu, Hiromitsu Kimura, Shiro Takahara
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X605510