Study protocol for the safety and efficacy of probiotic therapy on days alive and out of hospital in adult ICU patients: the multicentre, randomised, placebo-controlled Restoration Of gut microflora in Critical Illness Trial (ROCIT)

Introduction The effect of early and sustained administration of daily probiotic therapy on patients admitted to the intensive care unit (ICU) remains uncertain.Methods and analysis The Restoration Of gut microflora in Critical Illness Trial (ROCIT) study is a multicentre, randomised, placebo-contro...

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Main Authors: Tobias Strunk, David Broadhurst, Edward Litton, Anu Rammohan, Edward Raby, Laurens Manning, Matthew Anstey, Andy R Chapman, Andrew Currie, Janet Ferrier, Joel Gummer, Alisa Higgins, Jolene Lim, Erina Myers, Katrina Orr, Anne-Marie Palermo, Andrew Paparini, Susan Pellicano, Adrian Regli, Bernhard Richter, Sam Salman, Sharon Waterson, Brad Wibrow, Fiona M Wood
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/10/6/e035930.full