Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis

Differential expression of estrogen receptor subtypes and variants in ovarian cancer: effects on cell invasion, proliferation and prognosis

Abstract Background Due to the presence of both classical estrogen receptor (ERα) and another ER subtype (ERβ) in ovarian cancer, hormonal treatment is an attractive option. However, response to tamoxifen in ovarian cancer is modest. The presence of ERβ variants further complicated the issue. We hav...

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Bibliographic Details
Main Authors: Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Yan Wang, Thomas H. Y. Leung, Stephanie S. Liu, Annie N. Y. Cheung, Hextan Y. S. Ngan
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Cancer
Subjects:
Estrogen receptors
Ovarian cancer
Prognostic marker
Cell invasion and proliferation
Online Access:http://link.springer.com/article/10.1186/s12885-017-3601-1

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http://link.springer.com/article/10.1186/s12885-017-3601-1

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