Structural and functional insights into the mode of action of a universally conserved Obg GTPase.

Obg proteins are a family of P-loop GTPases, conserved from bacteria to human. The Obg protein in Escherichia coli (ObgE) has been implicated in many diverse cellular functions, with proposed molecular roles in two global processes, ribosome assembly and stringent response. Here, using pre-steady st...

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Bibliographic Details
Main Authors: Boya Feng, Chandra Sekhar Mandava, Qiang Guo, Jie Wang, Wei Cao, Ningning Li, Yixiao Zhang, Yanqing Zhang, Zhixin Wang, Jiawei Wu, Suparna Sanyal, Jianlin Lei, Ning Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC4028186?pdf=render