Semiallogenic fusions of MSI<sup>+ </sup>tumor cells and activated B cells induce MSI-specific T cell responses

Semiallogenic fusions of MSI<sup>+ </sup>tumor cells and activated B cells induce MSI-specific T cell responses

<p>Abstract</p> <p>Background</p> <p>Various strategies have been developed to transfer tumor-specific antigens into antigen presenting cells in order to induce cytotoxic T cell responses against tumor cells. One approach uses cellular vaccines based on fusions of autol...

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Bibliographic Details
Main Authors: Klier Ulrike, Garbe Yvette, Linnebacher Michael
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Cancer
Subjects:
Cell fusion
frameshift antigens
microsatellite instability
T cell epitopes
Online Access:http://www.biomedcentral.com/1471-2407/11/410

Internet

http://www.biomedcentral.com/1471-2407/11/410

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