Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

The "thrifty genotype" hypothesis proposes that the high prevalence of type 2 diabetes (T2D) in Native Americans and admixed Latin Americans has a genetic basis and reflects an evolutionary adaptation to a past low calorie/high exercise lifestyle. However, identification of the gene varian...

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Bibliographic Details
Main Authors: Desmond D Campbell, Maria V Parra, Constanza Duque, Natalia Gallego, Liliana Franco, Arti Tandon, Tábita Hünemeier, Cátira Bortolini, Alberto Villegas, Gabriel Bedoya, Mark I McCarthy, Alkes Price, David Reich, Andrés Ruiz-Linares
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3328483?pdf=render

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http://europepmc.org/articles/PMC3328483?pdf=render

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