TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection

TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection

<p>Abstract</p> <p>Background</p> <p>We have previously shown that toll-like receptor 3 (TLR3)-mediated signaling plays an important role in the induction of innate cytokine responses to Theiler's murine encephalomyelitis virus (TMEV) infection. In addition, cytoki...

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Bibliographic Details
Main Authors: Jin Young-Hee, Kaneyama Tomoki, Kang Min, Kang Hyun, Koh Chang-Sung, Kim Byung S
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Journal of Neuroinflammation
Subjects:
TLR3
TMEV
demyelination
CNS
T cell responses
Online Access:http://www.jneuroinflammation.com/content/8/1/178

Internet

http://www.jneuroinflammation.com/content/8/1/178

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