Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression

Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression

Abstract Background Exosomes mediated crosstalk between tumor cells and other stromal cells including tumor associated macrophages plays an essential role in reprogramming tumor microenvironment (TME) to facilitate tumor progression. However, the mechanism of tumor derived exosomes promotes bladder...

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Bibliographic Details
Main Authors: Ziming Jiang, Yiming Zhang, Yu Zhang, Zhankui Jia, Zhengguo Zhang, Jinjian Yang
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Cell Communication and Signaling
Subjects:
Exosomes
Bladder cancer
Tumor associated macrophages
Tumor microenvironment
Online Access:https://doi.org/10.1186/s12964-021-00768-1

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