NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma

NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma

Forkhead Box M1 (FOXM1) is an oncogenic transcription factor implicated in the pathogenesis of solid and hematologic cancers. In this study, we examined the significance of FOXM1 in NPM-ALK-positive anaplastic large cell lymphoma (NPM-ALK + ALCL), with a focus on how it interacts with NPM-ALK, which...

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Bibliographic Details
Main Authors: Moinul Haque, Jing Li, Yung-Hsing Huang, Meaad Almowaled, Carter J. Barger, Adam R. Karpf, Peng Wang, Will Chen, Suzanne D. Turner, Raymond Lai
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
anaplastic large cell lymphoma
NPM-ALK
FOXM1
gene regulation
thiostrepton
Online Access:https://www.mdpi.com/2072-6694/11/8/1119

Internet

https://www.mdpi.com/2072-6694/11/8/1119

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