Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

The discovery of the epigenetic regulation of transcription has provided a new source of mechanistic understanding to long lasting effects of chemicals. However, this information is still seldom exploited in a toxicological context and studies of chemical effect after washout remain rare. Here we st...

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Bibliographic Details
Main Authors: Alice Limonciel, Simone G. van Breda, Xiaoqi Jiang, Gregory D. Tredwell, Anja Wilmes, Lydia Aschauer, Alexandros P. Siskos, Agapios Sachinidis, Hector C. Keun, Annette Kopp-Schneider, Theo M. de Kok, Jos C. S. Kleinjans, Paul Jennings
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Genetics
Subjects:
recovery
persistence
epigenomics
stress responses
ochratoxin A
potassium bromate
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00558/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00558/full

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