Amino Acid Plasma Profiles from a Prolonged-Release Protein Substitute for Phenylketonuria: A Randomized, Single-Dose, Four-Way Crossover Trial in Healthy Volunteers

Amino Acid Plasma Profiles from a Prolonged-Release Protein Substitute for Phenylketonuria: A Randomized, Single-Dose, Four-Way Crossover Trial in Healthy Volunteers

Several disorders of amino acid (AA) metabolism are treated with a protein-restricted diet supplemented with specific AA mixtures. Delivery kinetics impacts AA absorption and plasma concentration profiles. We assessed plasma profiles after ingestion of an AA mixture engineered to prolong AA absorpti...

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Bibliographic Details
Main Authors: Mika Scheinin, Anna Barassi, Jouni Junnila, Zsófia Lovró, Giorgio Reiner, Essi Sarkkinen, Anita MacDonald
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Nutrients
Subjects:
disorders of amino acid metabolism
phenylketonuria
dietary management
amino acid absorption
bioequivalence
prolonged release
Online Access:https://www.mdpi.com/2072-6643/12/6/1653

Internet

https://www.mdpi.com/2072-6643/12/6/1653

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