CGRP outflow into jugular blood and cerebrospinal fluid and permeance for CGRP of rat dura mater

Abstract Background Calcitonin gene-related peptide (CGRP) is released from activated meningeal afferent fibres in the cranial dura mater, which likely accompanies severe headache attacks. Increased CGRP levels have been observed in different extracellular fluid compartments during primary headaches...

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Bibliographic Details
Main Authors: Miriam Risch, Birgit Vogler, Mária Dux, Karl Messlinger
Format: Article
Language:English
Published: BMC 2021-09-01
Series:The Journal of Headache and Pain
Subjects:
Online Access:https://doi.org/10.1186/s10194-021-01320-9