Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165

Triazolopeptides Inhibiting the Interaction between Neuropilin-1 and Vascular Endothelial Growth Factor-165

Inhibiting the interaction of neuropilin-1 (NRP-1) with vascular endothelial growth factor (VEGF) has become an interesting mechanism for potential anticancer therapies. In our previous works, we have obtained several submicromolar inhibitors of this interaction, including branched pentapeptides of...

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Bibliographic Details
Main Authors: Bartlomiej Fedorczyk, Piotr F. J. Lipiński, Anna K. Puszko, Dagmara Tymecka, Beata Wilenska, Wioleta Dudka, Gerard Y. Perret, Rafal Wieczorek, Aleksandra Misicka
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
peptidomimetics
VEGF<sub>165</sub>
neuropilin-1
molecular dynamics
structure–activity relationship
Online Access:https://www.mdpi.com/1420-3049/24/9/1756

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https://www.mdpi.com/1420-3049/24/9/1756

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