The role of ATP-binding cassette transporters in neuro-inflammation: relevance for bioactive lipids

The role of ATP-binding cassette transporters in neuro-inflammation: relevance for bioactive lipids

ATP-binding cassette (ABC) transporters are highly expressed by brain endothelial cells that form the blood-brain barrier (BBB). These efflux pumps play an important role in maintaining brain homeostasis as they actively hinder the entry of unwanted blood-derived compounds into the central nervous s...

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Bibliographic Details
Main Authors: Gijs eKooij, Jack evan Horssen, Veera Venkata Ratnam eBandaru, Norman J Haughey, Helga E De Vries
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Pharmacology
Subjects:
Astrocytes
ATP-Binding Cassette Transporters
Blood-Brain Barrier
Chemokines
Multiple Sclerosis
bioactive lipids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00074/full

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